Program Director with portfolio of grants to academic, commercial and nonprofit institutions, in biomedical technology, bioengineering, computation and instrumentation, and mental health and neuroscience.
Principal Investigator in the intramural research program of the National Cancer Institute, and Section Chief of the Metabolic Control Section. Directed a research group consisting of postdoctoral fellow, students and laboratory technicians. Conducted research on the cytochrome P450 enzymes that metabolize drugs and carcinogens, and elucidation of the cellular signaling pathways related to cancer. Scientific disciplines employed include: biochemistry, biophysics, pharmacology, structural biology, computational chemistry.
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PROFESSIONAL POSITIONS
| Independent Consultant | 2019- | |
| Program Director, Office of Technology Development and Coordination, National Institute of Mental Health, NIH | Manage extramural research grants in mental health, neurotechnologies and BRAIN Initiative | 2015-2019 |
| Program Director, Division of Biomedical Technology, Bioinformatics, and Computational Biology, National Institute of General Medical Sciences, NIH | Manage extramural program in development of innovative biomedical technologies | 2011-2015
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| Expert Consultant, Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute, NIH | Intramural research in metabolic biomarkers for cancer | 2011-2013 |
| Program Director, Division of Biomedical Technology, National Center for Research Resources, NIH | Manage extramural development of biomedical technologies | 2007-2011 |
| Director of Molecular Modeling Facility, Nanobiology Program, Center for Cancer Research, National Cancer Institute | Develop computer models of biological molecules | 2004-2007 |
| Principal Investigator and Chief of Metabolic Control Section, Laboratory of Metabolism, Center for Cancer Research, National Cancer Institute | Supervise laboratory research group in the areas of drug and carcinogen metabolism, and cancer signaling, via multidisciplinary approaches | 2000–2004 |
| Principal Investigator and Supervisory Research Chemist (appointed to equivalent of tenured Associate Professor in 1986), Laboratory of Molecular Carcinogenesis, National Cancer Institute | Conduct research to elucidate the structure and function of the enzymes that metabolize drugs and carcinogens | 1986–2000 |
| Senior Staff Fellow, Laboratory of Molecular Carcinogenesis, National Cancer Institute | Tenure track position in studies of xenobiotic metabolism. | 1982–1986 |
| Staff Fellow, Laboratory of Chemical Biology, National Institute of Arthritis, Metabolism, and Digestive Diseases, NIH | Tenure track researcher in biochemistry and biophysics of hemoglobin | 1979–1982 |